Cleavage of zearalenone by Trichosporon mycotoxinivorans to a 1 novel non - estrogenic metabolite . 2
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چکیده
novel non-estrogenic metabolite. 2 Elisavet Vekiru*, Christian Hametner, Rudolf Mitterbauer, Justyna Rechthaler Gerhard 3 Adam, Gerd Schatzmayr, Rudolf Krska and Rainer Schuhmacher 4 5 1 Christian Doppler Laboratory for Mycotoxin Research, Department for Agrobiotechnology (IFA 6 Tulln), University of Natural Resources and Applied Life Sciences Vienna, Konrad Lorenz Str. 7 20, 3430 Tulln, Austria 8 2 Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163, 9 1060 Vienna, Austria 10 3 Department of Applied Genetics and Cell Biology, University of Natural Resources and Applied 11 Life Sciences Vienna, Muthgasse 18, 1190 Vienna, Austria 12 4 University of Applied Sciences Wr. Neustadt, Konrad Lorenz Str. 10, 3430 Tulln, Austria 13 5 Biomin Research Center, Technopark 1, 3430 Tulln, Austria 14 15 * corresponding author 16 email: [email protected] 17 Phone:+43-2272-66280-409 18 Fax: +43-2272-66280-403 19 20 $ present address: Sandoz GmbH, Biochemiestraße 10, A-6250 Kundl, Austria 21 22 23 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Appl. Environ. Microbiol. doi:10.1128/AEM.01438-09 AEM Accepts, published online ahead of print on 29 January 2010
منابع مشابه
Cleavage of zearalenone by Trichosporon mycotoxinivorans to a novel nonestrogenic metabolite.
Zearalenone (ZON) is a potent estrogenic mycotoxin produced by several Fusarium species most frequently on maize and therefore can be found in food and animal feed. Since animal production performance is negatively affected by the presence of ZON, its detoxification in contaminated plant material or by-products of bioethanol production would be advantageous. Microbial biotransformation into non...
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Zearalenone (ZEA) as mycoestrogen is found in human foods and animal feeds. Its estrogenic potency depends on its biotransformation fate. The hepatic biotransformation of ZEA in two species of sturgeon fish (Acipenser persicus and Huso huso) was investigated. ZEA was incubated with the hepatic microsomal and post-mitochondrial sub-fractions in the presence of NADPH and the metabolites were dete...
متن کاملInterspecies variation in the hepatic biotransformation of zearalenone: Evidence for bio-inactivation of mycoestrogen zearalenone in sturgeon fish
Zearalenone (ZEA) as mycoestrogen is found in human foods and animal feeds. Its estrogenic potency depends on its biotransformation fate. The hepatic biotransformation of ZEA in two species of sturgeon fish (Acipenser persicus and Huso huso) was investigated. ZEA was incubated with the hepatic microsomal and post-mitochondrial sub-fractions in the presence of NADPH and the metabolites were dete...
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BACKGROUND Trichosporon mycotoxinivorans is a recently described yeast-like fungal organism and its association as a pathogen for patients with cystic fibrosis (CF) was reported previously. We show the clinical course of a CF patient over 9 years as well as the applications of modern molecular and proteomic identification techniques of this rare fungus. CASE PRESENTATION We present the case o...
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